Peptide Database

Peptide NameFGF-21

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length209 amino acids

Chemical FormulaC992H1541N273O303S5

DescriptionStandard

        HPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPMDSDETGFEHSGLWVSVLAGLLLGACQAGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS
    

Molecular Weight22299.82 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-9.62

Net Charge (pH 7.4) -10.27

Charge Density (pH 7.0) -0.0460

GRAVY Index-0.33

Hydrophobic Moment 0.65

Boman Index0.06

Instability Index58.61

Aliphatic Index 83.59

Aromaticity 0.0622

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0349088 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

Targetfibroblast growth factor receptor 1 (Human)

Activity4.5 nM

MethodEC50