Peptide Database

Peptide NameMagainin-2 [L6A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC111H174N30O29S

DescriptionStandard

        GIGKFAHSAKKFGKAFVGEIMNS
    

Molecular Weight2424.82 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1237

GRAVY Index-0.00

Hydrophobic Moment 0.67

Boman Index0.15

Instability Index-3.80

Aliphatic Index 59.57

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 957.13

LogP -8.91

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 84.0

Heavy Atoms 171.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001320 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (7% Hemolysis at 8 microg/ml

Activity8 μg/mL

MethodHemolysis

RECORD: Rec_0024656 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetKocuria rhizophila DSM 348

Activity256 μM

MethodMIC

RECORD: Rec_0032374 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli DH5alpha

Activity128 μM

MethodMIC

RECORD: Rec_0152044 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetFranconibacter helveticus DSM 18396

Activity128 μM

MethodMIC

RECORD: Rec_0227880 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus subtilis DSM 347

Activity32 μM

MethodMIC