Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length471 amino acids

Chemical FormulaC2347H3734N620O672S14

DescriptionStandard

        MNRLSWHTPALVVRTDISRAPPKGRRIGMELVKQAVLKETFPSWSGQESLSVVKVNYVISRLRINAVDFPETSASFIPGTGICLSVARASATISADWRMNAWLLKGKGEITVSISGLFISIIFNVSRDSTGHLSTLLHNCQLSIGSVKVKLSGRSSWIYSFLSGYLEKPIHTKLDKNLCLNIKYKIQMMDAQLKKHKVLSQIDTFAQVDYSLLSSPAVFKSHINLDLKGTVYPVGNHTDPPFMPAPFALPNQGDSMIYLGVSNYFLKSASLAYYRAGAFNITISEELATTFSLNTSLLKYFVSETSLSQAAACPVLLNLMATLPPAVSLNADRCVLQITGSVEVFAALPNSTTQYIFTGNLTASTTANLTITKQKLIISLLLKRFQFSLLHSNLGFPEQKSVVENFLSYALRRVVIPVINDKLGKGFPLLNLAHTSLTGPAIKMNQGHLVISTDVHYQPVDREDEDLHSHS
    

Molecular Weight51837.41 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)13.60

Net Charge (pH 7.4) 12.56

Charge Density (pH 7.0) 0.0289

GRAVY Index0.11

Hydrophobic Moment 0.73

Boman Index0.13

Instability Index34.32

Aliphatic Index 103.29

Aromaticity 0.0849

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312580 VERIFIED: NO

Provenance & Taxonomy

OrganismLepidothrix coronata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria