Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC499H825N141O142S10

DescriptionStandard

        MKAFLLTLAALVLLSQVTSGSAEKCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPNMLQRNRKDNPKICLELQKILNIQSNLDKEEQSWKHCTS
    

Molecular Weight11392.40 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.10

Charge Density (pH 7.0) 0.0860

GRAVY Index-0.37

Hydrophobic Moment 0.56

Boman Index-0.10

Instability Index51.08

Aliphatic Index 88.69

Aromaticity 0.0606

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4656.43

LogP -45.28

H-bond Donors 167.0

H-bond Acceptors 162.0

Rotatable Bonds 398.0

Heavy Atoms 792.0

Ring Count 12.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105190 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0312447 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence