Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length131 amino acids

Chemical FormulaC648H1045N181O196S9

DescriptionStandard

        MRLLLLALPILALLPQVIPAYGGEKKCWNKSGHCRKQCKDEEAMKEMCTNHRVCCIPDSKRHWQVPETPPTRSYDLTSVPFGVILTLVSTTHHVEVKSEKVTVKQSEVVHTTEISRPESFITAQSDEPDQS
    

Molecular Weight14795.91 Da

Isoelectric Point (pI)6.99

Net Charge (pH 7.0)-0.01

Net Charge (pH 7.4) -0.66

Charge Density (pH 7.0) -0.0001

GRAVY Index-0.41

Hydrophobic Moment 0.43

Boman Index-0.05

Instability Index64.98

Aliphatic Index 80.99

Aromaticity 0.0458

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6020.72

LogP -60.57

H-bond Donors 212.0

H-bond Acceptors 211.0

Rotatable Bonds 487.0

Heavy Atoms 1034.0

Ring Count 24.0

Amide Bonds 138.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277470 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence