Peptide Database

Peptide NameMacedovicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC90H138N24O32S4

DescriptionStandard

        ASSGWVCTLTQECGTFVCSCN
    

Molecular Weight2196.46 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.49

Charge Density (pH 7.0) -0.0591

GRAVY Index0.48

Hydrophobic Moment 0.32

Boman Index0.23

Instability Index79.91

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 905.97

LogP -13.45

H-bond Donors 36.0

H-bond Acceptors 35.0

Rotatable Bonds 67.0

Heavy Atoms 150.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420718 VERIFIED: YES

Provenance & Taxonomy

OrganismBifidobacterium longum [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)