Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC972H1544N272O258S9

DescriptionStandard

        PKALPMAREPMLLLAVTDFVANSAAFTYFTAGVLHRNISSNMLPRQFPLQLRTKNMGVFSPQLQERYRDQPMEIHLWARRQPLVSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTGGALPAPWTPLPALCQAQGLPVLQVKRLETLLKFGLWLFGVPRANSECCPHSVP
    

Molecular Weight21456.91 Da

Isoelectric Point (pI)10.15

Net Charge (pH 7.0)9.37

Net Charge (pH 7.4) 8.98

Charge Density (pH 7.0) 0.0483

GRAVY Index0.05

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index54.29

Aliphatic Index 95.52

Aromaticity 0.0773

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8340.46

LogP -101.57

H-bond Donors 288.0

H-bond Acceptors 281.0

Rotatable Bonds 676.0

Heavy Atoms 1511.0

Ring Count 43.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324812 VERIFIED: NO

Provenance & Taxonomy

OrganismFurnarius figulus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria