Peptide Database

Peptide NameVasostatin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC368H614N106O117S5

DescriptionStandard

        LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQ
    

Molecular Weight8555.78 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-2.07

Net Charge (pH 7.4) -2.42

Charge Density (pH 7.0) -0.0272

GRAVY Index-0.45

Hydrophobic Moment 0.73

Boman Index-0.09

Instability Index66.53

Aliphatic Index 94.87

Aromaticity 0.0132

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3617.11

LogP -37.57

H-bond Donors 122.0

H-bond Acceptors 122.0

Rotatable Bonds 294.0

Heavy Atoms 596.0

Ring Count 8.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112531 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyChromogranin/secretogranin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor

RECORD: Rec_0308226 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyVasostatin

Tax ID9606

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-38

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0368293 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyVasostatin

Tax ID9606

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-38

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory

Targetcells and noradrenergic neurons

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min