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MYP_027724
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Basic Information
Defensin-like protein 1 / Rs-AFP1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
51 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0401371 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus [Plant],Sinapis alba [Plant],Brassica juncea [Plant],Brassica rapa subsp. pkinensis [Plant]
Defensin
3726
Structure & Mods
linear peptide [Linear]
ambiguous/noncanonical residue annotation [Modified]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
X at 1 (reported unspecified residue)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Cytotoxic
Pyrenophora tritici-repentis
3 μg/mL
IC50
PMID8422949;1639777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0416495 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus [Plant],Sinapis alba [Plant],Brassica juncea [Plant],Brassica rapa subsp. pkinensis [Plant]
Defensin
3726
Structure & Mods
linear peptide [Linear]
ambiguous/noncanonical residue annotation [Modified]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
X at 1 (reported unspecified residue)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Cytotoxic
Alcaligenes eutrophus
PMID8422949;1639777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0417610 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus [Plant],Sinapis alba [Plant],Brassica juncea [Plant],Brassica rapa subsp. pkinensis [Plant]
Defensin
3726
Structure & Mods
linear peptide [Linear]
ambiguous/noncanonical residue annotation [Modified]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
X at 1 (reported unspecified residue)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Cytotoxic
Fusarium oxysporum f. sp. pisi
15 μg/mL
IC50
PMID8422949;1639777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0419597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Contains noncanonical/ambiguous residue(s); Contains X placeholder residue(s)
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US5750504A/en PatentUS 5750504 A
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