Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length127 amino acids

Chemical FormulaC663H993N177O191S3

DescriptionStandard

        MMYGTDKNAGVIPKEIADKLREKQYNNFDEFRNDFWKAVAETDYANEFLINGDPKNYYRMKNGGAPLVVSNQAINGSFTYQLHHIIPINQGGSVYSVDNLVVVTPRYHAEILIPEVHGYNGFKQFFR
    

Molecular Weight14595.24 Da

Isoelectric Point (pI)6.40

Net Charge (pH 7.0)-1.14

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0090

GRAVY Index-0.50

Hydrophobic Moment 0.73

Boman Index0.01

Instability Index13.51

Aliphatic Index 75.20

Aromaticity 0.1417

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 18910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5967.08

LogP -53.51

H-bond Donors 199.0

H-bond Acceptors 197.0

Rotatable Bonds 476.0

Heavy Atoms 1034.0

Ring Count 29.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028447 VERIFIED: NO

Provenance & Taxonomy

OrganismClostridium sp. AF36-18BH [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal