Peptide Database

Peptide NameConotoxin vill14a

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC120H190N34O36S6

DescriptionStandard

        GGLGRCIYNCMNSGGGLSFIQCKTMCY
    

Molecular Weight2877.39 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.72

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0636

GRAVY Index0.26

Hydrophobic Moment 0.62

Boman Index0.19

Instability Index31.56

Aliphatic Index 57.78

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1138.26

LogP -13.89

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 95.0

Heavy Atoms 196.0

Ring Count 3.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208278 VERIFIED: NO

Provenance & Taxonomy

OrganismCouns villepinii [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-26; 10-22

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0300520 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 22.2%, T 40.7%, C 37.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic