Peptide Database

Peptide NameAntimicrobial peptide Esculentin-1MS1

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC224H386N64O60S2

DescriptionStandard

        RISFKKGKGSWIKNGIIKGIKGIGKEIGLDVIRTGIDIAGCKIKGEC
    

Molecular Weight4999.98 Da

Isoelectric Point (pI)9.94

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.49

Charge Density (pH 7.0) 0.1434

GRAVY Index-0.04

Hydrophobic Moment 0.70

Boman Index0.05

Instability Index-15.47

Aliphatic Index 107.87

Aromaticity 0.0426

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2028.67

LogP -17.32

H-bond Donors 74.0

H-bond Acceptors 69.0

Rotatable Bonds 183.0

Heavy Atoms 350.0

Ring Count 3.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314595 VERIFIED: NO

Provenance & Taxonomy

OrganismHylarana maosuoensis [Animal]

FamilyEsculentin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant