Peptide Database

Peptide NameDefensin (Varisin A1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC340H561N113O93S10

DescriptionStandard

        MRGLCICLVFLLVCGLVSATAAAPAESEVAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
    

Molecular Weight8040.44 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)7.68

Net Charge (pH 7.4) 7.17

Charge Density (pH 7.0) 0.1037

GRAVY Index0.21

Hydrophobic Moment 0.72

Boman Index0.01

Instability Index68.22

Aliphatic Index 87.03

Aromaticity 0.0541

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3311.32

LogP -38.32

H-bond Donors 129.0

H-bond Acceptors 114.0

Rotatable Bonds 263.0

Heavy Atoms 556.0

Ring Count 9.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056159 VERIFIED: YES

Provenance & Taxonomy

OrganismDermacentor variabilis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria