Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC404H663N121O116S7

DescriptionStandard

        AECWSHGHCLLVCNDDEDHVLRCANRKRCCVPSRYVTMKPITIDYVLDWTTPTVPTTVPTTVRKRKKNKKTRPGVILLQTS
    

Molecular Weight9295.78 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)7.00

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.0864

GRAVY Index-0.46

Hydrophobic Moment 0.61

Boman Index-0.15

Instability Index50.02

Aliphatic Index 78.02

Aromaticity 0.0494

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3828.78

LogP -39.68

H-bond Donors 142.0

H-bond Acceptors 133.0

Rotatable Bonds 300.0

Heavy Atoms 648.0

Ring Count 15.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188362 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota monax [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence