MYP_027598
Polytheonamide B
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
not Standard
49 amino acids
-
contains X representing unresolved or non-standard residue
XGIGVLVAVLAGALANVGAGVNQVAGGNINVVGNINVNANVSVNMNQTT
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0245060
VERIFIED: YES
Provenance & Taxonomy
Theonella sp. [Animal]
Structure & Mods
linear peptide [Linear]
mixed D/L and noncanonical amino-acid peptide [Mixed]
5,5-dimethyl-2-oxohexanoyl (Ncap)
Alternating D/L residues; multiple nonproteinogenic amino acids (8 types) reported
Bio-Activity Profile
Cytotoxic
Anticancer
Ion-channel
Toxin
Solution NMR
RECORD: Rec_0433029
VERIFIED: YES
Provenance & Taxonomy
Theonella sp. [Animal]
Polytheonamide
Structure & Mods
linear peptide [Linear]
mixed D/L and noncanonical amino-acid peptide [Mixed]
5,5-dimethyl-2-oxohexanoyl (Ncap)
Alternating D/L residues; multiple nonproteinogenic amino acids; N-terminal 5,5-dimethyl-2-oxohexanoyl cap
Bio-Activity Profile
Cytotoxic
Anticancer
P388 mouse leukemia cells
0.098 nM
IC50 (XTT growth inhibition assay)