Peptide Database

Peptide NameDermaseptin-S13

Function Ontology

—

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC114H186N30O32S3

DescriptionStandard

        GLWSKIKEAAKTAGKMAMGFVNDM
    

Molecular Weight2585.07 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0733

GRAVY Index-0.06

Hydrophobic Moment 0.64

Boman Index0.11

Instability Index27.56

Aliphatic Index 61.25

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1010.64

LogP -8.40

H-bond Donors 35.0

H-bond Acceptors 37.0

Rotatable Bonds 90.0

Heavy Atoms 179.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0025054 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)