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MYP_027587
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Basic Information
Turgencin A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
36 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GPKTKAACKXACKLATCGKKPGGWKCKLCELGCDAV
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0334660 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 9144
6.3 μM
MIC
PMID31940927;32751755 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0335584 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aureobasidium pullulans
92.6 μg/mL
MIC
PMID31940927;32751755 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0341321 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Corynebacterium glutamicum ATCC 13032
0.4 μM
MIC
PMID31940927;32751755 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0342422 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X=MET-OXD
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 31940927 PMID31940927 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
RECORD: Rec_0355464 VERIFIED: YES
Provenance & Taxonomy
Synoicum turgens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
4.8 μM
IC50
PMID31940927;32751755 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31940927/
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