Peptide Database

Peptide NameHepcidin

Function Ontology

—

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC84H146N26O22S10

DescriptionStandard

        ICMFCCGCCKKARCGMCCKT
    

Molecular Weight2192.87 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)3.68

Net Charge (pH 7.4) 3.35

Charge Density (pH 7.0) 0.1839

GRAVY Index0.76

Hydrophobic Moment 0.35

Boman Index0.03

Instability Index25.80

Aliphatic Index 24.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 776.41

LogP -8.84

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 74.0

Heavy Atoms 142.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0160242 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyHepcidin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)