Peptide Database

Peptide NameBovine Beta-defensin 4

Function Ontology

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Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC206H330N72O49S8

DescriptionStandard

        QRVRNPQSCRWNMGVCIPFWCRVGMRQIGTCFGPRVPCCRR
    

Molecular Weight4855.80 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)7.70

Net Charge (pH 7.4) 7.41

Charge Density (pH 7.0) 0.1878

GRAVY Index-0.36

Hydrophobic Moment 0.57

Boman Index-0.20

Instability Index70.11

Aliphatic Index 47.32

Aromaticity 0.0976

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1974.85

LogP -20.90

H-bond Donors 77.0

H-bond Acceptors 65.0

Rotatable Bonds 152.0

Heavy Atoms 335.0

Ring Count 10.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155020 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)