Peptide Database

Peptide NameA. dichotoma defensin

Function Ontology

—

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC164H283N53O53S7

DescriptionStandard

        VTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGVCLCRK
    

Molecular Weight4069.78 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0441

GRAVY Index0.29

Hydrophobic Moment 0.49

Boman Index0.06

Instability Index23.41

Aliphatic Index 83.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1707.76

LogP -22.72

H-bond Donors 66.0

H-bond Acceptors 63.0

Rotatable Bonds 139.0

Heavy Atoms 277.0

Ring Count 1.0

Amide Bonds 41.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0123262 VERIFIED: YES

Provenance & Taxonomy

OrganismBombus terrestris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)