Peptide Database

Peptide NameL-amino acid oxidase bordonein-L (LAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length516 amino acids

Chemical FormulaC2650H4088N718O773S17

DescriptionStandard

        MNVFFMFSLLFLAALGSCAHDRNPLEECFRETDYEEFLEIARNGLTVTSNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERVGGRVRTYRKKDWYANLGPMRLPTKHRIVREYIRKFGLQLNEFFQENENAWYFIKNIRKRVREVKNNPGILEYPVKPSEEGKSAAQLYVESLRKVVKELKRTNCKYILDKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFGYEKRFDEIVGGMDQLPTSMYEAIKEKVQVHFNARVIEIQQNDRETKVTYQTSANEMSSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCKRKFWEDDGIRGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADIVINDLSLIHQLPKEDIQTFCRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPFKRIYFAGEYTAQFHGWIDSTIKSGLTAARDVNRASENPSGIHLSNDNEF
    

Molecular Weight58918.26 Da

Isoelectric Point (pI)8.00

Net Charge (pH 7.0)2.64

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0051

GRAVY Index-0.39

Hydrophobic Moment 0.94

Boman Index-0.03

Instability Index33.92

Aliphatic Index 78.62

Aromaticity 0.1182

Extinction Coeff. Reduced 66240.00

Extinction Coeff. Oxidized 66615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034808 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus terrificus [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Oxidoreductase Antiplatelet Cytolytic Toxin Cytotoxic Hemolytic

TargetLeishmania amazonensis