Peptide Database

Peptide NamePhakellistatin 19

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC51H71N9O10

DescriptionStandard

        IPWFPLTP
    

Molecular Weight970.16 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0300

GRAVY Index0.59

Hydrophobic Moment 0.09

Boman Index0.59

Instability Index25.62

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 276.67

LogP 1.75

H-bond Donors 8.0

H-bond Acceptors 10.0

Rotatable Bonds 21.0

Heavy Atoms 70.0

Ring Count 6.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297373 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

FamilyPhakellistatin

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: A549

Activity0.44 μM

MethodIC50

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