Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC257H429N71O87S5

DescriptionStandard

        MKSTNNQSISEIAAVNSLQEVSMEELDQIIGAGNGVVLTLTHECNLATWTKKLKCC
    

Molecular Weight6065.90 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.76

Charge Density (pH 7.0) -0.0434

GRAVY Index-0.02

Hydrophobic Moment 0.43

Boman Index0.08

Instability Index29.33

Aliphatic Index 97.50

Aromaticity 0.0179

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2583.19

LogP -30.54

H-bond Donors 90.0

H-bond Acceptors 91.0

Rotatable Bonds 210.0

Heavy Atoms 420.0

Ring Count 3.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0231079 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence