Peptide Database

Peptide NameFLAK01 AM

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC120H220N32O24

DescriptionStandard

        FALAAKALKKLAKKLKKLAKKAL
    

Molecular Weight2495.23 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.53

Charge Density (pH 7.0) 0.3805

GRAVY Index0.13

Hydrophobic Moment 0.82

Boman Index-0.07

Instability Index-8.89

Aliphatic Index 132.17

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 937.70

LogP -3.12

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 95.0

Heavy Atoms 176.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397587 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyFLAK / Hecate / Shiva peptide family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Anticancer

TargetHeLa

Activity82.0 μg/mL

MethodLD50 / MTT-MTS assay

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