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MYP_027467
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Basic Information
scFSEN
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
12 amino acids
C55H88N22O15S2
Standard
Sequence
KCGHKHQCAVHN
Physicochemical Analysis
1361.56 Da
8.91
2.00
1.61
0.1666
-1.15
0.32
-0.26
42.35
32.50
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
607.68
-7.81
22.0
22.0
45.0
94.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044520 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0114982 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0147627 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0151859 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
SPARC
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
2-8
Bio-Activity Profile
Control peptide
HUVEC / neuroblastoma-endothelial context
tumor progression assay
PaperAnti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors PMID20525313 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20525313/
RECORD: Rec_0242925 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
SPARC
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
2-8
Bio-Activity Profile
Control peptide
HUVEC / neuroblastoma-endothelial context
tube formation assay
PaperAnti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors PMID20525313 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20525313/
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