Peptide Database

Peptide NameS-type Pyocin domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length558 amino acids

Chemical FormulaC2694H4236N758O842S16

DescriptionStandard

        MTRALVRLGDKTTSGGEVISASSTIIEERNIALNGDMAWCPKETCNGPFQINGTAYYFAEDKPCVATGDRVLCNCKNNQVLGSTTIWVEDSPSDPFKEHRKRAAEWPINKVAAAAIIAIPVFAKSVLRGTGNTDAGESEEPQSNIGEMSFYQSQPTQPDPEPEQHAQAAKKKNAPPPEPPKKSLFDKVTGFFFGEAEAMPLPPPPVISGTAEAGMAASAGGATAKASQDAATALTHSMKRLSGPEVWNGRLAMNLPFVVMGAIIQSNLKGEQSDLLTPQNLLEVAHSKGTVPTRVRYNWITDDDSGRLKAVGYHTTAASGRDQVRVRMLERQTDGSYEFWGDERSDKSLITWTPANTPGSQNGWNTGNNNPQAGTVTIPGLEHPDIQNVTITTTPLPEEKDFRDYILVFPGNVHPPIYIYLSKPPVELLEVELYIDFNGRSRQGEYEADHMPSAAAVRLYYQRLYPDADEKELEMLAKEVAAIVIPKGVHRKISETYGGRNREPGRVERDSRDLRAAADRNFDVIKPALKESGITEEKLEAARAKIHELNESVELYKK
    

Molecular Weight61228.07 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-11.56

Net Charge (pH 7.4) -12.53

Charge Density (pH 7.0) -0.0207

GRAVY Index-0.55

Hydrophobic Moment 0.76

Boman Index-0.05

Instability Index35.95

Aliphatic Index 72.62

Aromaticity 0.0699

Extinction Coeff. Reduced 67840.00

Extinction Coeff. Oxidized 68090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0269025 VERIFIED: YES

Provenance & Taxonomy

OrganismErwiniaceae bacterium PD-1 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli