Peptide Database

Peptide NameBeta-defensin 114 (Beta-defensin 14, DEFB-14; Defensin, beta 114; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC217H356N64O71S7

DescriptionStandard

        DRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
    

Molecular Weight5221.99 Da

Isoelectric Point (pI)6.37

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0067

GRAVY Index-1.01

Hydrophobic Moment 0.70

Boman Index-0.41

Instability Index67.11

Aliphatic Index 54.42

Aromaticity 0.0698

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2253.80

LogP -22.68

H-bond Donors 86.0

H-bond Acceptors 78.0

Rotatable Bonds 183.0

Heavy Atoms 359.0

Ring Count 4.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408161 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

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