Peptide Database

Peptide Namebeta-Defensin, DEFB13

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC178H257N47O52S6

DescriptionStandard

        RECQLVRGACKPECNSWEYVYYYCNVNPCCAVWE
    

Molecular Weight4079.62 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0379

GRAVY Index-0.39

Hydrophobic Moment 0.52

Boman Index-0.03

Instability Index46.14

Aliphatic Index 51.47

Aromaticity 0.1765

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1610.15

LogP -13.43

H-bond Donors 61.0

H-bond Acceptors 57.0

Rotatable Bonds 123.0

Heavy Atoms 283.0

Ring Count 10.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131428 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-29; 10-24; 14-30

Bio-Activity Profile

Function

Antimicrobial