Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC168H271N49O57S2

DescriptionStandard

        KCNTATCVTQRLADFLVRSSNTIGAVYSPTNVGSNTY
    

Molecular Weight3953.37 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.11

Hydrophobic Moment 0.68

Boman Index0.02

Instability Index10.41

Aliphatic Index 71.08

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1747.46

LogP -25.41

H-bond Donors 64.0

H-bond Acceptors 61.0

Rotatable Bonds 125.0

Heavy Atoms 276.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213932 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudopodoces humilis [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)