Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2294H3641N617O649S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAILEKELAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFQLPYSRITPISNEGLQVSISNAFTEVDGDWRVKFLFVRDRGSFNLKVENVYIKIILGLGSDPSGKPTISTSDCSARISKVQVLFSGRLGWLYNLFHSAIESRLRKILEHKVCDSVVKSVNSALQTYLQTLPVTARIDDKTGIDYSLVAPPRTTAQSLDADLKGEFYSLGHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKDVGFRLDTSVFSAFIPQLEEMYPNMTMKFRLSAPAAPFMTIGPEGISLQPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVRMLQSLMNVLTSSTLLPRLNARLDEGFPLPLLDRIQLSNILVKFHQNFLLLGADVHFQPQ
    

Molecular Weight50568.84 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)7.29

Net Charge (pH 7.4) 6.48

Charge Density (pH 7.0) 0.0160

GRAVY Index0.09

Hydrophobic Moment 0.67

Boman Index0.10

Instability Index35.66

Aliphatic Index 104.96

Aromaticity 0.0899

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186523 VERIFIED: NO

Provenance & Taxonomy

OrganismCisticola juncidis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria