Peptide Database

Peptide NameAlefacept

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length457 amino acids

Chemical FormulaC2306H3594N610O694S26

DescriptionStandard

        CFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDEDEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSIILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTNSNRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPQVKFNWYVDGVQVHNAKTKPREQQYNSTYRVVSVLTVLHQNWLDGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight51800.57 Da

Isoelectric Point (pI)7.86

Net Charge (pH 7.0)2.69

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0059

GRAVY Index-0.43

Hydrophobic Moment 0.66

Boman Index-0.02

Instability Index43.01

Aliphatic Index 74.75

Aromaticity 0.0919

Extinction Coeff. Reduced 62800.00

Extinction Coeff. Oxidized 63800.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339816 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory

TargetCHO

Half-Life270 hrs