Peptide Database

Peptide NameCycloviolacin Y2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC100H145N25O32S6

DescriptionStandard

        CGETCFTGICFTAGCSCNPWPTC
    

Molecular Weight2401.76 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0564

GRAVY Index0.48

Hydrophobic Moment 0.18

Boman Index0.29

Instability Index10.57

Aliphatic Index 21.30

Aromaticity 0.1304

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 883.27

LogP -11.92

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 67.0

Heavy Atoms 163.0

Ring Count 6.0

Amide Bonds 23.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0024878 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)