MYP_027348
Basic Information
Brevinin-1H with transferred Rana-box, Brevinin-1Ha
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antifungal
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Standard
21 amino acids
C109H185N27O24S2
Standard
Sequence
FALGAVTCLIRTKCKVLPKLF
Physicochemical Analysis
2321.93 Da
9.85
3.74
3.50
0.1780
1.08
0.57
0.26
11.70
130.00
0.0952
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.95
-3.43
31.0
30.0
76.0
162.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0362089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
64 μM
MBC
RECORD: Rec_0379328 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human squamous lung carcinoma NCI-H157
278.9 μM
IC50
RECORD: Rec_0382290 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Amolops hainanensis [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Horse blood cells: only over 20% at a concentration of 128 μM
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