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MYP_027348
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Basic Information
Brevinin-1H with transferred Rana-box, Brevinin-1Ha
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C109H185N27O24S2
Standard
Sequence
FALGAVTCLIRTKCKVLPKLF
Physicochemical Analysis
2321.93 Da
9.85
3.74
3.50
0.1780
1.08
0.57
0.26
11.70
130.00
0.0952
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.95
-3.43
31.0
30.0
76.0
162.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0270591 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Amolops hainanensis [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 32812694 PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0285863 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 12493
128 μM
MBC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0314945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
128 μM
MBC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0353984 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
128 μM
MIC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0357516 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MDA-MB-435S
214.7 μM
IC50
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
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