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MYP_027348
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Basic Information
Brevinin-1H with transferred Rana-box, Brevinin-1Ha
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C109H185N27O24S2
Standard
Sequence
FALGAVTCLIRTKCKVLPKLF
Physicochemical Analysis
2321.93 Da
9.85
3.74
3.50
0.1780
1.08
0.57
0.26
11.70
130.00
0.0952
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
816.95
-3.43
31.0
30.0
76.0
162.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0192196 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
128 μM
MBC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0199213 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
128 μM
MBC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0237071 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
128 μM
MIC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0250260 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 12493
128 μM
MIC
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
RECORD: Rec_0256411 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human prostate adenocarcinoma PC-3
186.9 μM
IC50
PMID32812694 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32812694/
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