Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC159H243N47O49S6

DescriptionStandard

        DHYKCAKNGGTCHYSSCPLFSKIEGTCYGGRAKCC
    

Molecular Weight3789.31 Da

Isoelectric Point (pI)8.63

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0821

GRAVY Index-0.53

Hydrophobic Moment 0.39

Boman Index-0.07

Instability Index70.07

Aliphatic Index 28.00

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1546.80

LogP -19.99

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 122.0

Heavy Atoms 261.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073050 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)