Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1198 amino acids

Chemical FormulaC5846H9119N1667O1808S32

DescriptionStandard

        MDNWSALFDGQTRYVLDINDSTVKADVLRFRGREALSEPFRWDIEFTSLHANIPPEQVLMKYASLRMRGGKNVHGMVTRLEWLSTSRDQSHYRLTLSSRLTLLGYTRQCAVFQNLSVPEVVEQVLRKHGLEGPDFEFRLERTYPARELITQWRETDLQFIQRILSEVGIYWRTEMDDVHGLDTCILADSQLDYQFDVQLPYSEPSGLFDGAADSVWDVRTWHNIATGTVATRDYNYRTATTPMDATVSVRSDAVTTGAHYRYTAPYRDAGDDTSPEPETESGAFYARIHHERELSRSARIHLFSNTGHLTPGQVLEPQGDVITALKEGVILTLVTFRGARDSRLHVSVWGVPYTERYCFRPAEIPRPLIPGTLPARIESREKNDIYAHLDEQGRYRVRLDFDRDATDPGYGYLWLRMAKPTAGETSGWHTPLTDGTEVAIAYSNGDIDLPYIACALYDSEHPDHVTRDNHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKSQLNSGHMVDSQGQRRGTGAELRTDEHGVIRAGKGLFVSADAQPKAQGEALDRDAALKEIDRLNQQLQQLEIAAEKAQALKADVDSQIQMFAQRLKPLNEALLMTAPEGMALTSGEDMQLAATKNVAVNAGGDISAGVTGNLTALAGEKLGLFARSGQLSLKSGEGAIDVQAQNASLRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGANAPAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSENNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIRPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTPKLHDEIHYRR
    

Molecular Weight132708.11 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-29.56

Net Charge (pH 7.4) -31.84

Charge Density (pH 7.0) -0.0247

GRAVY Index-0.51

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index33.51

Aliphatic Index 75.20

Aromaticity 0.0801

Extinction Coeff. Reduced 172580.00

Extinction Coeff. Oxidized 173080.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325858 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella diarizonae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID59204

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli