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MYP_027286
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Basic Information
TsAP-S2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C99H170N22O18S
Standard
Sequence
FLGMIPKLIKKLIKAFK
Physicochemical Analysis
1988.61 Da
10.60
4.76
4.54
0.2797
0.75
0.87
0.24
-21.10
143.53
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
650.23
1.47
22.0
24.0
71.0
140.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044837 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Derivative of TsAP-1, Brazilian yellow scorpion venom peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
HI-57
0.83 μM
IC50
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
RECORD: Rec_0059100 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0092782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Derivative of TsAP-1, Brazilian yellow scorpion venom peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
H-838
1.6 μM
IC50
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
RECORD: Rec_0158063 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacteria: Escherichia coli
5 μM
MIC
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
RECORD: Rec_0191415 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fungi: Candida albicans
2.5 μM
MIC
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
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