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MYP_027285
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Basic Information
PQ (De Novo Synthesis)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C121H179N41O19S2
Standard
Sequence
IHKFWRCRRRFCRWFKHI
Physicochemical Analysis
2576.11 Da
11.84
6.91
6.58
0.3840
-0.89
0.89
-0.44
140.98
43.33
0.2778
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1008.50
-3.73
42.0
30.0
83.0
183.0
9.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0355214 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. pyocyaneum ATCC 27853
8 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0357312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
16 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0381507 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
8 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0393436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300
8 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0406083 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
The cell viability of intestinal epithelial cells (IPEC-J2) induced by PQ is 68
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
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