Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC841H1373N237O251S7

DescriptionStandard

        MKTQRDGPSLGRWSLVLLLLGLTMPLAVTGRILSYQEAVLHAVDGLNQRSLDANLYRLLNLDPRPTMDGDPDTPKPVSFTVKETVCPRTIQRSPEECDFKEDGLVKWCVGTVTLNQAKDSFDISCDKDKRNVARLGDILQKAREKIEGGLKKLVQKIKDFFGKFAPRTES
    

Molecular Weight19044.79 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.57

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.41

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index40.19

Aliphatic Index 89.41

Aromaticity 0.0588

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7906.72

LogP -84.49

H-bond Donors 276.0

H-bond Acceptors 263.0

Rotatable Bonds 645.0

Heavy Atoms 1336.0

Ring Count 23.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151875 VERIFIED: YES

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyCathelicidin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0202129 VERIFIED: YES