Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length306 amino acids

Chemical FormulaC1566H2445N423O439S6

DescriptionStandard

        TNPGFMVRITQAGLDYAHQHGIAILEKELAQLKLPDISGDSRVLRVGKVHYEFSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFIRDHGSFNLKVENVYMKIILKLGSDTTGKPTISTWDCSAHISKVRVLFSGKLGWLYNLFHSFIESRLRKNLEQKICDNVAKSVQNELQKRLRTLPVTARIDDKTGLDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAAIAYHKAGALVFEITEAMIPKDAGFRLDTSVFSAFIPQVSSL
    

Molecular Weight34414.13 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)7.28

Net Charge (pH 7.4) 6.48

Charge Density (pH 7.0) 0.0238

GRAVY Index-0.09

Hydrophobic Moment 0.68

Boman Index0.05

Instability Index32.50

Aliphatic Index 94.35

Aromaticity 0.1078

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040127 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvietta virens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria