Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC83H142N26O23S8

DescriptionStandard

        ICVFCCGCCKNARCGICCKT
    

Molecular Weight2128.70 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.1339

GRAVY Index1.02

Hydrophobic Moment 0.39

Boman Index0.13

Instability Index1.49

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 793.48

LogP -9.90

H-bond Donors 36.0

H-bond Acceptors 34.0

Rotatable Bonds 69.0

Heavy Atoms 140.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352855 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyHepcidin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)