Peptide Database

Peptide NameSecukinumab

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length457 amino acids

Chemical FormulaC2268H3485N597O686S16

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAASGFTFSNYWMNWVRQAPGKGLEWVAAINQDGSEKYYVGSVKGRFTISRDNAKNSLYLQMNSLRVEDTAVYYCVRDYYDILTDYYIHYWYFDLWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight50603.56 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 2.66

Charge Density (pH 7.0) 0.0079

GRAVY Index-0.38

Hydrophobic Moment 0.61

Boman Index0.02

Instability Index46.30

Aliphatic Index 72.60

Aromaticity 0.1050

Extinction Coeff. Reduced 90760.00

Extinction Coeff. Oxidized 91385.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0158591 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory

Half-Life22-31 days