Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

—

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC122H192N32O38S6

DescriptionStandard

        PCGESCVWIPCISGIAGCSCSNKVCYLN
    

Molecular Weight2907.41 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-0.10

Net Charge (pH 7.4) -0.25

Charge Density (pH 7.0) -0.0036

GRAVY Index0.65

Hydrophobic Moment 0.27

Boman Index0.28

Instability Index30.40

Aliphatic Index 80.00

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1092.68

LogP -13.21

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 89.0

Heavy Atoms 198.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0357623 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)