Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC754H1178N216O220S7

DescriptionStandard

        MMVSKVQFNPRSRTDAIFVHCSATKPSQDIGVDTIRMWHKQQGWLDVGYHFVIKRDGTVEEGRPVDVVGSHVKDWNSRSVGVCLVGGIDAKGKFEANFTPAQMNALRNKLAELKALYPQADIKAHHDVAPKACPSFDLQLWLSTNELVTSDHG
    

Molecular Weight17013.19 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.45

Charge Density (pH 7.0) 0.0072

GRAVY Index-0.33

Hydrophobic Moment 0.58

Boman Index-0.00

Instability Index41.08

Aliphatic Index 78.95

Aromaticity 0.0784

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6987.07

LogP -70.16

H-bond Donors 242.0

H-bond Acceptors 235.0

Rotatable Bonds 560.0

Heavy Atoms 1197.0

Ring Count 30.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081002 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage CLB_P1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic