Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H268N50O58S2

DescriptionStandard

        KCNTATCATQRLANFLVRSSNNFGTILSSTDVGSNTY
    

Molecular Weight3956.33 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.20

Hydrophobic Moment 0.67

Boman Index-0.02

Instability Index17.88

Aliphatic Index 65.95

Aromaticity 0.0811

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1799.34

LogP -28.02

H-bond Donors 66.0

H-bond Acceptors 62.0

Rotatable Bonds 129.0

Heavy Atoms 276.0

Ring Count 3.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381836 VERIFIED: YES

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)