Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length741 amino acids

Chemical FormulaC3466H5430N942O1085S17

DescriptionStandard

        MSTVLYIHPPHGCYVFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYNHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISITGSGSQLYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEILSSLGAAVGRVIASLGATATAGTAGPMVAAASAILFSPAAGGGSDRVPGRDLNAMFALNAQLLAGPDVKIEPGATSVNLPERGQLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGLYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGELPDNKVMIDRLENILNGGLQATDTDLRFYTHEIRELERYRNLGVKDGVIPDNYDEVWNNTHTATLEDYKINEKTQPLYTPEAEEAYRKAEEGK
    

Molecular Weight78200.96 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-29.17

Net Charge (pH 7.4) -30.32

Charge Density (pH 7.0) -0.0394

GRAVY Index-0.27

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index34.52

Aliphatic Index 78.69

Aromaticity 0.0648

Extinction Coeff. Reduced 78270.00

Extinction Coeff. Oxidized 78395.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013868 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli