Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC478H754N116O140S7

DescriptionStandard

        MKLFLVLFILLFEVPTDGAGLRKCFNDTIGYCRKKCKIGEIYEVECLSGKLCCINEEESKRYLEAHKLQEPDEKYLLGDYDITPTNSIFTIA
    

Molecular Weight10590.25 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-3.45

Net Charge (pH 7.4) -3.85

Charge Density (pH 7.0) -0.0375

GRAVY Index-0.08

Hydrophobic Moment 0.44

Boman Index0.05

Instability Index36.81

Aliphatic Index 97.50

Aromaticity 0.1087

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4128.46

LogP -29.23

H-bond Donors 147.0

H-bond Acceptors 145.0

Rotatable Bonds 359.0

Heavy Atoms 741.0

Ring Count 14.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038389 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence