Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length586 amino acids

Chemical FormulaC2827H4504N778O874S6

DescriptionStandard

        MTVGGGGGWDSPVNDDRKGGNDRDDGKGGSAVDFSKNPEKQAIVNPYLAIALPMPVYPIYGTPGFTINTVAIETGLAKISAAIGRALPVAGRLLGVTVGAMWPSSTAPSSLDSIYNQAHQQALAQLAAQQGVLNKGYNVTAMPAGLVSSLPVSEIKSLPTAPASLLAQSVINTEFSQRQLTLTQPATNAPVANIPVVKAEKTAVPGVYSAKIIAGEPAFQIKVDNTKPALAQNPPKVKDDIQVSSFLSTPVADTHHAFIDFGSDHEPVYVSLSKIVTAEEEKKQVEEAKRREQEWLLRHPVAAAERKVQDAINAEAEAERGVKSAELALNNLKTSPNGLTLADPVKYPAKAEWPEIYDVPEYGDYAQIKFNFSVLVDSVAKLNALLAQGAGALLTDEISWHDVITKYSVNNLSQDMLNDPSETMFVLGDVYKEQALEYYGYLRSELLKSKELISNAEKSLIIAIESRKKAEQDKKTADQKLKDEQETKRKGVRETGHKYHPNPDTSEIKGLGELKEGRAKTPKQGGGGKRARWIGEKGRKIYEWDSQHGELEGYRASDGQHLGAFDPKTGKQLKPADPKRNIKKYL
    

Molecular Weight63567.08 Da

Isoelectric Point (pI)6.83

Net Charge (pH 7.0)-0.55

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0009

GRAVY Index-0.48

Hydrophobic Moment 0.74

Boman Index-0.02

Instability Index39.17

Aliphatic Index 83.29

Aromaticity 0.0648

Extinction Coeff. Reduced 68300.00

Extinction Coeff. Oxidized 68300.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416795 VERIFIED: NO

Provenance & Taxonomy

OrganismPectobacterium polaris [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence