Peptide Database

Peptide NameFz7-21

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC81H111N17O23S2

DescriptionStandard

        LPSDDLEFWCHVMY
    

Molecular Weight1754.98 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.16

Net Charge (pH 7.4) -3.43

Charge Density (pH 7.0) -0.2256

GRAVY Index0.05

Hydrophobic Moment 0.30

Boman Index0.24

Instability Index77.00

Aliphatic Index 76.43

Aromaticity 0.2143

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 629.66

LogP -1.67

H-bond Donors 22.0

H-bond Acceptors 23.0

Rotatable Bonds 51.0

Heavy Atoms 123.0

Ring Count 6.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192672 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetFZD7 (Human)

Activity100 nM

MethodIC50